The Integrin Alpha V + Beta 5 Antibody, Cy5.5 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to ITGAV. This antibody recognizes Human, and Mouse antigen. The Integrin Alpha V + Beta 5 Antibody, Cy5.5 Conjugated has been validated for the following applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions